Efek Neuroprotektif Magnesium Sulfat Antenatal pada Prematuritas

Oleh :

dr. Felicia

Magnesium sulfat yang diberikan antenatal diduga mampu memberikan efek neuroprotektif pada janin yang terancam mengalami prematuritas. Prevalensi bayi lahir prematur meningkat setiap tahun, dimana diperkirakan 1 dari 10 bayi lahir prematur setiap tahun.

Kelahiran prematur adalah kelahiran pada usia gestasi < 37 minggu. Bayi yang lahir prematur berisiko mengalami gangguan neurodevelopmental seperti cerebral palsy (CP), disfungsi motorik, gangguan sensorineural, epilepsi, dan gangguan kognitif yang berpengaruh pada performa akademik dan pekerjaan di tahap kehidupan selanjutnya.[1–6,19]

Cerebral palsy (CP) adalah gangguan neurodevelopmental yang sering ditemukan pada bayi yang lahir prematur. Dilaporkan bahwa 35-40% bayi yang lahir prematur mengalami cerebral palsy. Risiko ini meningkat dengan semakin rendahnya usia gestasi saat lahir.[2–5]

(Konten ini khusus untuk dokter. Registrasi untuk baca selengkapnya)

Referensi

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