Untung Rugi Roux-en-Y Gastric Bypass

Oleh :

dr. Reren Ramanda

Roux-en-Y Gastric Bypass (RYGB) adalah salah satu teknik pembedahan untuk menurunkan berat badan pada pasien obesitas morbid. Teknik ini adalah teknik bariatric surgery yang paling banyak digunakan. Namun, tindakan ini diduga berkaitan dengan kerugian jangka panjang, seperti defisiensi vitamin dan mineral. Sekitar 47% pasien obesitas yang menjalani tindakan operatif, menggunakan teknik RYGB.[1,2]

Mekanisme Penurunan Berat Badan pada Roux-en-Y Gastric Bypass

Mekanisme penurunan berat badan pada Roux-en-Y Gastric Bypass (RYGB) ada dua, yaitu restriksi gaster dan malabsorbsi ringan. Operasi dilakukan dengan memisahkan sedikit bagian gaster, lalu membuat kantong kecil (pouch) berukuran sekitar 10–20 mL dari bagian gaster yang telah dipisahkan tadi. Kantong kecil inilah yang nantinya akan menjadi lambung produktif pasien.[1,3]

(Konten ini khusus untuk dokter. Registrasi untuk baca selengkapnya)

Referensi

1. Saber AA. Bariatric Surgery. Medscape. 2021 https://emedicine.medscape.com/article/197081-overview
2. Dimitrov DV, Ivanov V, Atanasova M. Advantages of bariatric medicine for individualized prevention and treatments: multidisciplinary approach in body culture and prevention of obesity and diabetes. EPMA J. 2011 Sep;2(3):271-6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405394/
3. Umemura A, Lee WJ, Sasaki A, et al. History and current status of bariatric and metabolic surgeries in East Asia. Asian J Endosc Surg 8 (2015) 268-274. https://onlinelibrary.wiley.com/doi/epdf/10.1111/ases.12190
4. Le Roux CW, Welbourn R, Werling M, et al. Gut Hormones as Mediators of Appetite and Weight Loss After Roux-en-Y Gastric Bypass. Annals of Surgery, 2007. 246(5): 780–785. doi:10.1097/sla.0b013e3180caa3e3
5. Maciejewski ML, Aterburn DE, Scoyoc LV, et al. Bariatric surgery and long-term Durability of Weight Loss. JAMA Surg. 2016 Nov 1; 151(11): 1046–1055. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112115/pdf/nihms-814620.pdf
6. Halperin F, Ding SA, Simonson DC, et al. Roux-en-Y gastric bypass surgery or lifestyle with intensive medical management in patients with type 2 diabetes feasibility and 1-year results of a randomized clinical trial. JAMA Surg. 2014;149(7):716-726. https://jamanetwork.com/journals/jamasurgery/fullarticle/1876617
7. Hayoz C, Hermann T, Raptis DA, et al. Comparison of metabolic outcomes in patients undergoing laparoscopic roux-en-Y gastric bypass versus sleeve gastrectomy - a systematic review and meta-analysis of randomised controlled trials. Swiss Med Wkly. 2018 Jul 5;148:w14633. https://www.ncbi.nlm.nih.gov/pubmed/30035801
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11. Li YJ, Han Y, He B. Effects of bariatric surgery on obese polycystic ovary syndrome: a systematic review and meta-analysis. Surgery for Obesity and Related Diseases. In press April 3, 2019. https://www.soard.org/article/S1550-7289(19)30098-X/fulltext
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13. Jamal M, Gunay Y, Capper A, et al. Roux-en-Y gastric bypass ameliorates polycystic ovary syndrome and dramatically improves conception rates: a 9-year analysis. Surgery for Obesity and Related Diseases. July–August, 2012 Volume 8, Issue 4, Pages 440–444. https://www.soard.org/article/S1550-7289(11)00706-4/fulltext
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15. Mazidi M, Gao HK, Li L, et al. Effects of Roux-en-Y gastric bypass on insulin secretion and sensitivity, glucose homeostasis, and diabetic control: A prospective cohort study in Chinese patients. SURGERY. May 2017 Volume 161, Issue 5, Pages 1423–1429. Available from : https://www.surgjournal.com/article/S0039-6060(16)30796-6/fulltext
16. Kwon O, Lee YJ, Yu JH, et al. The recovery of beta-cell function is critical for antidiabetic outcomes of gastric bypass in asian subjects with type 2 diabetes and a body mass index below 30. Obesity Surgery. February 2017, Volume 27, Issue 2, pp 541–544; https://link.springer.com/article/10.1007%2Fs11695-016-2455-y
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