Dampak Terapi Testosteron Terhadap Otot

Oleh :

dr.Putra Rizki Sp.KO

Secara fisiologis, testosterone memicu peningkatan sintesis protein otot dan merangsang pertumbuhan sel otot. Terapi testosterone umumnya digunakan di praktik untuk memperbaiki tanda dan gejala defisiensi testosterone, seperti perbaikan fungsi seksual, fungsi otot, anemia, serta bone mineral density (BMD) tulang vertebra dan femoral. Meski begitu, dewasa ini testosterone kerap digunakan untuk pembesaran otot pada individu sehat.[1,2]

Seiring bertambahnya usia, secara alami akan terjadi penurunan massa otot, yang hingga level tertentu akan menurunkan pula fungsi otot dan kualitas hidup. Beberapa penelitian memanfaatkan terapi testosterone sebagai alternatif penanganan sarkopenia pada usia lanjut. Meski begitu, hasil penelitian-penelitian ini belum konsisten sehingga efek terapi testosterone dalam meningkatkan kualitas otot masih belum jelas.[3]

Kurangnya Basis Bukti Efikasi Testosterone untuk Menambah Massa Otot pada Individu Sehat

(Konten ini khusus untuk dokter. Registrasi untuk baca selengkapnya)

Referensi

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