Kombinasi obat yang mengandung dekongestan, antihistamin, dan analgesik sering digunakan untuk penatalaksanaan common cold. Obat-obat ini biasanya dijual secara over-the-counter (OTC), sehingga distribusinya di masyarakat sangat luas. Berbagai uji klinis kemudian dilakukan untuk mengevaluasi efektivitas kombinasi obat-obat ini dalam mengatasi gejala common cold dan juga menilai efek sampingnya.[1-3]
Common cold adalah kumpulan gejala infeksi saluran pernapasan atas yang biasanya disebabkan oleh bermacam virus dan bersifat self-limiting. Gejala common cold dapat berupa rhinorrhea, hidung tersumbat, bersin, batuk, tenggorokan tidak nyaman, dan demam ringan. Selain itu, pasien juga mungkin mengalami sakit kepala ringan, malaise, myalgia, dan artralgia. Penatalaksanaan common cold bertujuan untuk mengatasi simtom dan mempersingkat durasi common cold.[3,4]
Kombinasi Dekongestan-Antihistamin-Analgesik yang Sering Digunakan untuk Tata Laksana Common Cold
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Referensi
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13. Kiran MD, Vakharia MP, Pawaskar JL, et al. Efficacy and safety of a fixed dose combination of paracetamol, chlorpheniramine maleate and phenylephrine in treatment of common cold: a phase IV, open-labelled, multi-centric study. Int J Basic Clin Pharmacol. 2019;8(1):34-38.
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