Pemeriksaan Biomarker untuk Cedera Otak Traumatik

Oleh :

dr. Irwan Supriyanto PhD SpKJ

Biomarker untuk menentukan diagnosis dan prognosis cedera otak traumatik merupakan topik yang terus diteliti dan dikembangkan. Saat ini, cedera otak traumatik diklasifikasikan menggunakan kombinasi hasil temuan klinis dan radiologis.

Walau demikian, terdapat keterbatasan dari kombinasi keduanya, misalnya pada cedera aksonal difus (diffuse axonal injury). Pada kondisi ini, hanya ditemukan kelainan minor pada hasil CT yang tidak sesuai dengan kondisi klinis dan prognosis yang buruk.

Cedera Otak Traumatik

Cedera otak traumatik/ traumatic brain injury (TBI) adalah jejas struktural pada otak atau gangguan fungsi fisiologis otak yang diinduksi oleh trauma akibat kekuatan dari luar. TBI bisa diklasifikasikan sebagai ringan, sedang, dan berat.[1,2]

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Referensi

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