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Etiologi Alopecia Androgenetik pada Pria
Etiologi alopecia androgenetik pada pria atau male pattern hair loss (MPHL) telah diketahui melibatkan faktor genetik dan hormonal. Berbagai kondisi eksternal dapat menjadi faktor risiko yang mempengaruhi siklus pertumbuhan rambut.
Etiologi alopecia androgenetik pada pria dan wanita kurang lebih serupa. Etiologi yang dibahas dalam artikel ini adalah alopecia androgenetik pada pria. Etiologi alopecia androgenetik wanita akan dibahas pada artikel terpisah.[1,3,4,8,14,15]
Faktor Genetik
Referensi
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2. Mysore V, Parthasaradhi A, Kharkar RD, et al. Expert consensus on the management of Androgenetic Alopecia in India. International journal of trichology, 2019. 11(3), 101–106. https://doi.org/10.4103/ijt.ijt_24_19
3. Feinstein RP. Androgenetic Alopecia Treatment & Management. Medscape, 2022. https://emedicine.medscape.com/article/1070167-overview
4. British Association of Dermatologists. Androgenetic Alopecia. 2015. https://www.bad.org.uk/shared/get-file.ashx?id=153&itemtype=document
8. Zubair Z, Kantamaneni K, Jalla K, et al. Prevalence of Low Serum Vitamin D Levels in Patients Presenting With Androgenetic Alopecia: A Review. Cureus, 2021. 13(12): e20431. doi:10.7759/cureus.20431. https://www.cureus.com/articles/71349-prevalence-of-low-serum-vitamin-d-levels-in-patients-presenting-with-androgenetic-alopecia-a-review
9. English RS Jr. A hypothetical pathogenesis model for androgenic alopecia: clarifying the dihydrotestosterone paradox and rate-limiting recovery factors. Med Hypotheses. 2018 Feb;111:73-81. doi: 10.1016/j.mehy.2017.12.027.
10. Martinez-Jacobo L, Villarreal-Villarreal CD, Ortiz-López R, Ocampo-Candiani J, Rojas-Martínez A. Genetic and molecular aspects of androgenetic alopecia. Indian J Dermatol Venereol Leprol, 2018. 84:263-268. https://ijdvl.com/genetic-and-molecular-aspects-of-androgenetic-alopecia/
11. Danlan Fu, Junfei Huang, Kaitao Li, Yuxin Chen, Ye He, Yang Sun, Yilong Guo, Lijuan Du, Qian Qu, Yong Miao, Zhiqi Hu. Dihydrotestosterone-induced hair regrowth inhibition by activating androgen receptor in C57BL6 mice simulates androgenetic alopecia. Biomedicine & Pharmacotherapy, 2021. Volume 137, 2021,111247, ISSN 0753-3322. https://doi.org/10.1016/j.biopha.2021.111247.
12. Martinez-Jacobo L, Ancer-Arellano C, I, Ortiz-Lopez R, Salinas-Santander M, Villarreal-Villarreal C, D, Ancer-Rodriguez J, Camacho-Zamora B, Zomosa-Signoret V, Medina-De la Garza C, E, Ocampo-Candiani J, Rojas-Martinez A. Evaluation of the Expression of Genes Associated with Inflammation and Apoptosis in Androgenetic Alopecia by Targeted RNA-Seq. Skin Appendage Disord, 2018;4:268-273. doi: 10.1159/000484530
13. Stephanie A. Tatalaksana Alopecia Androgenetik. Cermin Dunia Kedokteran, 2018. CDK-267/ vol. 45 no. 8. http://www.cdkjournal.com/index.php/CDK/article/viewFile/623/398
14. Salman KE, Altunay IK, Kucukunal NA, Cerman AA. Frequency, severity and related factors of androgenetic alopecia in dermatology outpatient clinic: hospital-based cross-sectional study in Turkey. Anais brasileiros de dermatologia, 2017. 92(1), 35–40. https://doi.org/10.1590/abd1806-4841.20175241
15. Cranwell W, Sinclair R. Male Androgenetic Alopecia. [Updated 2016 Feb 29]. In: Feingold KR, Anawalt B, Boyce A, et al., editors. Endotext. South Dartmouth (MA): MDText.com, Inc.; 2000-. https://www.ncbi.nlm.nih.gov/books/NBK278957/
16. Chen X, Liu B, Li Y, et al. Dihydrotestosterone Regulates Hair Growth Through the Wnt/β-Catenin Pathway in C57BL/6 Mice and In Vitro Organ Culture. Front Pharmacol. 2020;10:1528. Published 2020 Jan 23. doi:10.3389/fphar.2019.01528
17. Fabbrocini G, Cantelli M, Masarà A, et al. Female pattern hair loss: A clinical, pathophysiologic, and therapeutic review. International journal of women's dermatology, 2018. 4(4), 203–211. https://doi.org/10.1016/j.ijwd.2018.05.001
18. Carmina E, Azziz R, Bergfeld W, et al. Female Pattern Hair Loss and Androgen Excess: A Report From the Multidisciplinary Androgen Excess and PCOS Committee. The Journal of clinical endocrinology and metabolism, 2018. 104(7), 2875–2891. https://doi.org/10.1210/jc.2018-02548
19. Starace M, Orlando G, Alessandrini A, Piraccini BM. Female Androgenetic Alopecia: An Update on Diagnosis and Management. American journal of clinical dermatology, 2020. 21(1), 69–84. https://doi.org/10.1007/s40257-019-00479-x
20. Dharam Kumar KC, Kishan Kumar YH, Neladimmanahally V. Association of Androgenetic Alopecia with Metabolic Syndrome: A Case-control Study on 100 Patients in a Tertiary Care Hospital in South India. Indian J Endocrinol Metab. 2018 Mar-Apr;22(2):196-199. doi: 10.4103/ijem.IJEM_650_17.
21. Ozbas Gok S, Akin Belli A, Dervis E. Is There Really Relationship between Androgenetic Alopecia and Metabolic Syndrome? Dermatol Res Pract. 2015;2015:980310. doi: 10.1155/2015/980310.
22. Pradhan M. A Study of Serum Ferritin Level in Female Patient with Alopecia. Journal of College of Medical Sciences-Nepal, 2018. 14. 116. 10.3126/jcmsn.v14i2.20217. https://www.researchgate.net/publication/326475251_A_Study_of_Serum_Ferritin_Level_in_Female_Patient_with_Alopecia/citation/download
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