Diagnosis Juvenile Angiofibroma

Oleh :

dr.Nailla Fariq Alfiani

Diagnosis juvenile angiofibroma diawali dengan anamnesis gejala yang umum terjadi seperti epistaksis berulang dan obstruksi hidung unilateral, yang sering disertai massa di nasofaring yang dapat teraba melalui endoskopi.[3,11]

Pencitraan menggunakan computed tomography (CT) bisa menilai keterlibatan tulang dan struktur paranasal, sementara magnetic resonance imaging (MRI) dapat melihat ekstensi intrakranial dan vaskularisasi tumor, yang penting untuk perencanaan bedah. Biopsi umumnya dihindari karena risiko perdarahan masif, mengingat tumor bersifat sangat vaskular.[10,11,13,15]

Anamnesis

Referensi

1. Nakayama S, Nishio J, Aoki M, Koga K, Nabeshima K, Yamamoto T. Angiofibroma of soft tissue: Current status of pathology and genetics. Histol Histopathol. 2022 Aug;37(8):717-722. doi: 10.14670/HH-18-444.
2. Josef Shargorodsky. Juvenile angiofibroma. UF Health. 2023. https://ufhealth.org/conditions-and-treatments/juvenile-angiofibroma
3. Shah UK. Juvenile angiofibroma. MSD Manual. 2025. https://www.msdmanuals.com/professional/pediatrics/miscellaneous-ear-nose-and-throat-disorders-in-children/juvenile-angiofibromas
4. Newman M, Nguyen TBV, McHugh T, Reddy K, Sommer DD. Early-onset juvenile nasopharyngeal angiofibroma (JNA): a systematic review. J Otolaryngol Head Neck Surg. 2023 Dec 19;52(1):85. doi: 10.1186/s40463-023-00687-w.
5. Alla SSM, Alla D, Ratheesh V, Ramineni PK, Singh A, K V, Siddiqua A. Juvenile Nasopharyngeal Angiofibroma: A Case Report of a Rare Adolescent Head and Neck Tumor. Cureus. 2023 Jan 11;15(1):e33633. doi: 10.7759/cureus.33633.
6. Arulappan LAS. Extranasopharyngeal angiofibroma in an adolescent male: a case report. International Journal of Otorhinolaryngology and Head and Neck Surgery. 2019;5(5):1416–1418. https://doi.org/10.18203/issn.2454-5929.ijohns20193895
8. Fang R, Sun W, Shi J, Xu R, Peng L, Lai Y, Chen F, Wen Y, Wen W, Li J. Risk Factors and Characteristics of the Recurrence of Juvenile Nasopharyngeal Angiofibroma: A 22-Year Experience With 123 Cases at a Tertiary Center. Clin Exp Otorhinolaryngol. 2022 Nov;15(4):364-371. doi: 10.21053/ceo.2022.01053.
10. Baba A, Kurokawa R, Kurokawa M, Srinivasan A. MRI features of sinonasal tract angiofibroma/juvenile nasopharyngeal angiofibroma: Case series and systematic review. J Neuroimaging. 2023 Sep-Oct;33(5):675-687. doi: 10.1111/jon.13116.
11. Tork CA, Winters R, Simpson DL. Nasopharyngeal Angiofibroma. StatPearls Publishing; 2025. https://www.ncbi.nlm.nih.gov/books/NBK545240/
12. Alrusayyis D, Alotaibi JK, Almutarii R, Almolani FM, Al-Ahmari M, Alkhatib A, Almomen A. Five challenging presentations of juvenile nasopharyngeal angiofibroma: our experience in the diagnosis and endoscopic surgical management. J Surg Case Rep. 2025 Feb 28;2025(2):rjaf055. doi: 10.1093/jscr/rjaf055.
13. García-Fernández A, et al. Endoscopic surgical management of juvenile nasopharyngeal angiofibroma: Correlating tumour characteristics, risk of hemorrhage, and recurrence. Auris, Nasus, Larynx. 2024;51(6):940–946. https://doi.org/10.1016/j.anl.2024.09.004
15. Doody J, Adil EA, Trenor CC, Cunningham MJ. The Genetic and Molecular Determinants of Juvenile Nasopharyngeal Angiofibroma: A Systematic Review. Annals of Otology, Rhinology & Laryngology. 2019;128(11):1061-1072. doi:10.1177/0003489419850194. https://journals.sagepub.com/doi/abs/10.1177/0003489419850194
16. Pieter NAL, et al. Juvenile nasopharyngeal angiofibroma characteristics at Dr. Wahidin Sudirohusodo Hospital Makassar 2011–2021. In Proceedings of the 19th Otorhinolaryngology Head and Neck Surgery National Congress (PERHATIKL 2022), Advances in Health Sciences Research. 2022. https://doi.org/10.2991/978-94-6463-280-4_37
17. Dewi YA, et al. Management of juvenile nasopharyngeal angiofibroma in a referral hospital in West Java, Indonesia. Althea Medical Journal. 2020;7(1):45–50. https://doi.org/10.15850/amj.v7n1.1787
18. Giorgianni A, Molinaro S, Agosti E, et al. Twenty Years of Experience in Juvenile Nasopharyngeal Angiofibroma (JNA) Preoperative Endovascular Embolization: An Effective Procedure with a Low Complications Rate. J Clin Med. 2021 Aug 31;10(17):3926. doi: 10.3390/jcm10173926.
20. Granados Gonzalez GA, et al. Image Findings of Juvenile angiofibroma , A Benign Tumor With Aggressive Behavior [Poster presentation, ECR 2024, Poster C-23015]. European Congress of Radiology. 2024. https://dx.doi.org/10.26044/ecr2024/C-23015

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Diagnosis Juvenile Angiofibroma

Referensi

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