Epidemiologi Arteriovenous Malformation (AVM)

Oleh :

dr.Nailla Fariq Alfiani

Data epidemiologi menunjukkan angka kejadian beragan arteriovenous malformation (AVM) di setiap negara, dengan prevalensi berkisar antara 0,2 hingga 1,4 per 100.000 penduduk per tahun. Jumlah kasus AVM pada susunan saraf pusat lebih banyak dibandingkan AVM perifer.[1,14,16-20]

Global

Angka kejadian AVM serebral berdasarkan data prospektif New York Islands AVM Study di Amerika Serikat adalah sekitar 1,34 per 100.000 orang-tahun, meskipun prevalensinya secara nasional belum diketahui. Peningkatan penggunaan MRI otak dengan ambang pemeriksaan yang rendah menyebabkan lebih banyak kasus terdeteksi sebelum terjadi perdarahan.

Referensi

1. Bokhari MR, Bokhari SRA. Arteriovenous Malformation of the Brain. StatPearls Publishing; 2025 Jan-. https://www.ncbi.nlm.nih.gov/books/NBK430744/
4. Sen S. Arteriovenous Malformations. Medscape. Nov 2021. https://emedicine.medscape.com/article/1160167-overview#a5
14. Swatan JP, Islamiyah WR, Sani AF, et al. Initial Clinical Presentations and Morphological Characteristics of Cerebral AVM in A Tertiary Health Center – Does Gender Matter?, World Neurosurgery, 2025. Volume 27, 100475, ISSN 2590-1397. 2025. https://doi.org/10.1016/j.wnsx.2025.100475.
16. Sugiyama T, Grasso G, Torregrossa F, et al. Current Concepts and Perspectives on Brain Arteriovenous Malformations: A Review of Pathogenesis and Multidisciplinary Treatment. World Neurosurgery, 2022. Volume 159, 2022, Pages 314-326, ISSN 1878-8750. https://doi.org/10.1016/j.wneu.2021.07.106.
17. Shen Y, Wang Z, Yang X, et al. Novel Classification for Simple Peripheral Arteriovenous Malformations Based on Anatomic Localization: Prevalence Data From the Tertiary Referral Center in China. Front Cardiovasc Med. 2022. 9:935313. doi: 10.3389/fcvm.2022.935313. https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2022.935313/full
18. Pelayo-Salazar ME, Montenegro-Rosales HA, Balderrama-Bañares JL, et al. Clinical and Anatomic Description of Patients with Arteriovenous Malformation Treated with Endovascular Therapy in A Mexican Population. Journal of cerebrovascular and endovascular neurosurgery, 2023. 25(1), 36–49. https://doi.org/10.7461/jcen.2023.E2022.06.003
19. Brunozzi D, Alaraj A, Unruptured Brain Arteriovenous Malformation Risk Stratification. Journal of NeuroInterventional Surgery, 2025. doi: 10.1136/jnis-2024-022779. https://jnis.bmj.com/content/neurintsurg/early/2025/04/30/jnis-2024-022779.full.pdf
20. Silva AHD, James G. Natural History and Clinical Manifestation of Pediatric Brain Arteriovenous Malformations. Journal of Korean Neurosurgical Society, 2024. 67(3): 280-288. https://doi.org/10.3340/jkns.2024.0037
21. Darlan D, Arham A, Kemal MAR. Profile of The Brain Arteriovenous Malformation at National Brain Center Hospital in 2015 – 2016: Epidemiological study. Indonesian Journal of Neurosurgery, 2021. 4(3): 116-119. DOI: 10.15562/ijn.v4i3.186.
22. Garcia-Espinosa P, Botello-Hernández E, Torres-Hernández G, et al. Predictors of Cerebral Arteriovenous Malformation Mortality: A Single-center, Five-year Retrospective Study. Int J Med Students, 2021. Vol 9 | Issue 3 DOI 10.5195/ijms.2021.88. 2021
23. Pohjola A, Asikainen A, Kaprio J, et al. Sudden Prehospital Deaths from Brain Arteriovenous Malformations. Neurology Journal, 2025. volume 105, number 2, pp e213818. Doi: 10.1212/WNL.0000000000213818.

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